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I read about
an herbal product called Amrit® in Coping Magazine (for cancer patients).
Is there any science to this stuff? Is this product safe for me to take
when I am on chemotherapy?
You are very
wise to try to learn as much as you can about any complementary therapy,
such as this herbal product, that you might choose to help fight your
cancer. I refer to that as making an informed decision rather than an
emotional decision.
Ayurveda is the
ancient Indian system of medicine and surgery. The word Ayurveda in
Sanskrit (root language of Indian Subcontinent) literally means "Life
Science". Research is underway regarding many aspects of Ayurveda,
including the health benefits of the Ayurvedic preparation called Maharishi
Amrit Kalash (also abbreviated as MAK-4&5), which is made from extracts
of 44 herbs and fruits and based on a ancient formula. Amrit® literally
means "food for immortality".
Amrit Protection
System® (called Amrit® for short) consists of two products,
called MAK-4 and MAK-5. MAK-4 is available as a thick nectar consistency
paste, which is taken orally by mouth. One month supply of MAK-4 in
2-21 oz jars costs $79. MAK-5 is available in tablet form only and
is
taken orally as well. 120 tablets for a monthly supply cost $70. (Costs
quoted are current as of the date this FAQ was posted but are always
changing.)
Several studies
testing Amrit's® anti-cancer activity have been conducted. The following
two examples have been published in a peer-reviewed journal, as have
several other in vitro and animal studies.
(1) The herbal mixture MAK-4 was tested for anticarcinogenic properties
against artificially induced mammary tumors in rats. This study showed
that diet supplemented with MAK-4 protected the rats against artificially
induced carcinogenesis by reducing both tumor incidence and multiplicity
during initiation and promotion phases (The Pharmacologist, Vol. 34,
No. 3, p.184, 1992).
(2) MAK-4 and MAK-5 have also shown to reverse the malignant process
in murine neuroblastoma cells tissue culture under laboratory conditions
(Neuropharmacology, Vol.31, No.6, pp.599-607, 1992).
There are several
additional reported research studies that have tested Amrit® in
patients undergoing chemotherapy:
(1) 62 patients with various types of cancer, Rao, R.S., Deo, M.G.,
and Sanghvi, L.D. Proceedings of XVI International Cancer Congress.
Bologna, Italy: Monduzzi, Editore, 1994: pp.3099-3102,
(2) 92 breast cancer patients - All India Institute of Medical Science,
Srivastava A, Samaiya A, et.al., Abstract no 172,1999,
(3) 129 breast cancer patients - FASEB Experimental Biology 2000 Meeting,
San Diego, CA
However, it is
very important to note that these research studies have only been presented
at scientific conferences, and have not yet been published in peer-reviewed
journals (a necessary step for the widespread acceptance of the data
presented.)
Several Internet
sites and other media outlets are promoting Amrit® as a formula
that will prevent side effects secondary to chemotherapy without reducing
the effectiveness of the chemotherapy. However, without being able to
see all the data upon which these claims are based, I cannot really
validate the scientific strength of these statements at this time. Thus,
I am unable to answer your question of whether Amrit® is safe to
take during chemotherapy at this time.
As an additional
point of clarification, several web sites discussing Amrit® mention
that it contains high amounts of the antioxidants Vitamin E and Vitamin
C. Other web sites state that the formula has an antioxidant capacity
1000x greater than that of Vitamin C or E. The ingredients as listed
on Amrit's main web site do not include any additional antioxidants
in the formula, and no nutritional analysis of Amrit's® Vitamin
C and Vitamin E contents could be found published on the Internet. It
is very common for phytochemicals found in plants to have significant
antioxidant activity, far beyond that of the plant's antioxidant nutrient
content. However, it is not known if Amrit's® anti-cancer activity
shown in the animal and in vitro studies is due to its antioxidant actions
or the multiple other potential anti-cancer mechanisms that this complex
formula may provide.
An Email inquiry
and a telephone call have been made to the company that manufactures
Amrit®, asking for the latest research and more detailed information
about these studies and claims that the formula does not diminish chemotherapy's
effects. In the meantime, I cannot yet recommend this product, but I
will provide updated information on my web site as the company provides
me with further data.
The benefits
of Amrit® for cancer patients, while very intriguing, will remain
unproven until large-scale human studies are undertaken and published
in peer-reviewed journals, with enough data available for the oncology
community to review, analyze and evaluate. Accordingly, the scientific
community will then be able to better establish the validity of the
Amrit® formula's benefits.
Ultimately, the
choice is yours to make regarding all the therapeutic options you utilize
to fight your cancer. I will admit that "unproven does not equal
disproven". Gather as much information as you can, make your choices,
and then believe in those therapies with 1000% conviction. However,
if you do choose to use Amrit® or any other complementary therapy
(acupuncture for example) as a component of your personal cancer healing
plan, I strongly recommend that you discuss that choice with your oncologist
and have that healing modality documented in your medical record.
Best wishes to
you.
This question
and answer was researched and developed by Mitali Kapila, MSc, MS, RD.
The information posted here was written under the direction of and edited
by Diana Dyer, MS, RD.
Posted 9/02,
Updated 2/04, Updated 11/05
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These questions and
answers are intended to be of a general informative nature. Please
consult with the Registered Dietitian in your cancer center or your
health care provider for nutritional advice that can be individualized
to your specific medical condition.
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